Senior Scientist, Integrative Computational Biology
$140,800 and $211,200
Apply (opens in a new tab)Senior Scientist, Integrative Computational Biology
Posted 2 days ago
SENIORITY
Senior
SALARY
$140,800 and $211,200
About the role
- Scientific Evidence and Portfolio Advancement: Partner with CI Leads to develop integrated evidence packages, presentations, and scientific narratives that inform project reviews and portfolio decisions from PreLO through Candidate Selection.
- In Silico Evidence Generation: Generate, integrate, and document robust in silico evidence addressing disease biology, target rationale, NTC MoA, translational relevance, patient segmentation, biomarkers, and differentiation from competing approaches.
- Computational Analysis: Apply advanced computational methods, including multi-omics and AI/ML approaches, to analyze internal and external datasets, generate actionable scientific evidence, and inform discovery and portfolio decisions.
- Scientific Collaboration: Communicate assumptions, results, uncertainties, and recommendations effectively; incorporate feedback from CI Leads and partner functions; and contribute constructively to multidisciplinary discussions.
- Ph.D. in Bioinformatics, Computational Biology, Immunology, Molecular Biology, or a related discipline, with minimal 2 years of relevant postdoctoral experience, preferably with experience in drug discovery and development within the pharmaceutical industry.
- Expertise in bioinformatics and the analysis of large-scale biological datasets, such as single-cell RNA-seq, spatial transcriptomics, and proteomics.
- Strong understanding of disease biology and mechanisms, preferably in immunology, pulmonology, gastroenterology, rheumatology, and/or dermatology.
- Experience integrating multiple data types and lines of evidence to assess target biology, MoA, translational relevance, biomarkers, or patient segments.
- Proficiency in reproducible data analysis and visualization using relevant programming languages and computational environments; experience with machine learning/AI methods for biological data is desirable.
- Ability to critically evaluate data quality, analytical assumptions, uncertainty, and the limitations of computational evidence.
- Demonstrated ability to translate complex findings into concise, decision-relevant insights and presentations for multidisciplinary drug discovery teams.
- Excellent communication, interpersonal, organizational, and presentation skills.
- Proven ability to work independently on assigned deliverables while collaborating closely with CI Leads and cross-functional colleagues.
- Must be legally authorized to work in the United States without restriction.
- Must be willing to take a drug test and post-offer physical (if required).
- Must be 18 years of age or older. Compensation DataThis position offers a base salary typically between $140,800 and $211,200. The position may be eligible for a role specific variable or performance-based bonus and or other compensation elements. For an overview of our benefits please click here.
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