Senior Director, Clinical Science, Thoracic Oncology (Hybrid)
merck sharp dohme msdEast Boston (MA)
Senior Director, Clinical Science, Thoracic Oncology (Hybrid)
Posted today
merck sharp dohme msdEast Boston (MA)
SENIORITY
Manager
About the role
Overview:
In this role you provide strategic Clinical Science leadership across thoracic oncology, guiding multiple studies, programs, and assets to align with portfolio objectives. You collaborate with Section Heads, Asset Leads, and cross-functional teams to shape development plans and standardize scientific practices. You apply deep knowledge of disease biology and the evolving treatment landscape to inform study design, endpoints, and data interpretation, driving cross-asset insights. You will lead and develop Clinical Science talent in a matrix environment and contribute to governance discussions that shape the lung oncology portfolio. This position offers the chance to influence strategy, data‑g Compensation / Benefits annual bonus long-term incentive medical, dental, vision insurance 401(k) paid holidays vacation
Responsibilities:
Provide strategic Clinical Science leadership across disease area, studies, programs, and assets Contribute to disease area strategy with input on opportunities, risks, and data implications Collaborate with cross-functional leaders to align Clinical Science activities with program objectives Apply expert knowledge of therapeutic focus, biology, and endpoints to inform planning and interpretation Standardize Clinical Science approaches and promote consistency across the portfolio Support cross-study and cross-asset integration of scientific insights for development decisions Lead efforts in portfolio governance and scientific content for governance discussions Manage and develop Directors, Principal Scientists, and Clinical Scientists within a matrix environment Partner with Clinical Operations, Regulatory Affairs, Biostatistics, Data Management, Drug Safety, Translational Medicine, Medical Affairs Ensure compliance with regulatory requirements and drive continuous improvement Communicate clinical and scientific issues to stakeholders and leadership Translate portfolio priorities into Clinical Science strategies, capabilities, and resources Foster accountability, inclusion, and high performance within the team
Key requirements:
Significant experience in Clinical Development/Clinical Science within pharma/biotech Demonstrated leadership across multiple studies, programs, or assets Deep therapeutic area expertise in thoracic oncology, including disease biology and endpoints Strong understanding of oncology trial design, development strategy, and data interpretation Experience contributing to disease area strategy, portfolio discussions, and cross-program planning Experience with regulatory submissions and health authority interactions Proven ability to work effectively in a cross-functional, matrix environment Excellent communication, influence, and executive presentation skills Demonstrated people leadership, coaching, and staff development leadership communication influence Clinical Development Oncology Clinical Trial Planning
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