Overview Are you driven to push the boundaries of neuroscience and play a strategic role in advancing CNS drug delivery? This is an incredible opportunity to join an innovative biotech team dedicated to transforming treatments for neurological diseases through next-generation therapeutic delivery technologies.
As aPrincipal Scientist, you will:
Leadpreclinical pharmacology and bioanalytical programs, shaping IND-enabling studies and guiding the development of CNS-targeted therapeutics.
Collaborate closely with cross-functional teams and external partners, influencing key decisions from concept to regulatory submission.
Essential Job Duties:
Design and execute in vivo pharmacology studies supporting discovery and IND-enabling research.
Oversee bioanalytical strategies using ELISA, MSD, qPCR, LC/MS, and histology for PK/PD and biodistribution.
Interpret preclinical data and contribute to regulatory documentation.
Serve as a key scientific lead in interactions with CROs, academic collaborators, and internal stakeholders.
Mentor junior scientists and contribute to the strategic direction of CNS programs.
Qualifications:
Ph.D. in Pharmacology, Neuroscience, Bioengineering, or related discipline.
8+ years of biotech/pharma experience with biologics (antibodies, oligonucleotides, peptides).
Proven track record in IND-enabling research and bioanalytical development.
Strong understanding of CNS disease models and drug delivery systems.
Excellent leadership, organization, and communication skills. Compensation
Target Salary - $180K - 200K+ before bonus and benefits Be part of a mission-driven team shaping the future of CNS therapeutics. Work in a fast-paced, collaborative environment where innovation meets impact and where your science drives meaningful change.
How to apply:
Interested? Apply now or reach out directly: Location Los Angeles, CATorrance, CA and surrounding areas may be considered as applicable locations. Notes Referrals increase your chances of interviewing at HW3. This description represents current responsibilities and requirements. EEO statements and other required notices: included as applicable.
