Cleveland Clinic Research, home to basic science, translational and clinical research at the Cleveland Clinic, in collaboration with the nationally ranked Pediatric Diseases Institute, invites applications for a leader in the field to design and direct a translational program in interventional therapyin pediatricdisease. We are seeking applicants for full time positions at the Associate or Full Professor level who have expertise in gene therapy, hematology, stem cell therapy and/or pediatric oncology and have experience translating their work into clinical studies. We seek a translational scientist with a distinguished record of innovation in hematology or immunotherapeutics to serve as both an independent laboratory lead and an institution cornerstone for gene therapy advancement in pediatric disease. The investigator is expected to lead and drive a productive and innovative laboratory research program that translates into the design and implementation of novel therapeutics for pediatric disease in the Center for Childhood Diseases of the Cleveland Clinic Health System. The Center is a state-of-the-art center that focuses on research in the development of new hematologic and/or immunotherapeutics for a broad array of childhood diseases. Leadership responsibilities include developing a team-based translational research program and guiding investigator-initiated interventional trials across a broad range of disciplines in pediatric diseases. In this role the investigator will serve as the primary institutional resource for the development of a comprehensive gene therapy trial pipeline. Key responsibilities include providing strategic leadership in navigating complex FDA interactions, overseeing/advising pre-IND and IND-enabling studies, and ensuring institutional compliance with evolving gene therapy regulations. Expertise with building translational infrastructure is highly desirable, and manufacturing strategies necessary to advance a diverse array of gene therapy candidates into clinical trials. The candidate should hold anMD, PhD, or both. Responsibilities for candidates with MDs may include clinical care and the candidatewill be expected to lead clinical trial development.
