Skip to main content
David Careers

Senior Principal CMC Scientist

Posted 3 days ago

cslWaltham (MA)
Natural Sciences ManagersResearch and Development in Biotechnology

SENIORITY

Manager

SALARY

$160000 - 220000 per year

Apply (opens in a new tab)

About the role

Serves as a senior scientific expert guiding CMC strategy for innovative biologics, especially cell and gene therapies. Provides technical recommendations across process and analytical development, manufacturing, technology transfer, stability, regulatory and quality considerations, and lifecycle management while collaborating with internal teams and external partners. Guide CMC strategy for innovative biologics and advanced therapeutic programs. Assess process development, analytical development, characterization, manufacturing, technology transfer, stability, control strategy, and lifecycle management. Develop data-driven technical recommendations aligned with program stage, scientific evidence, regulatory expectations, quality requirements, and supply needs. Provide technical oversight of external development and manufacturing partners, including review of deliverables, issue investigations, and risk mitigation. Contribute scientific expertise to cross-functional program teams and communicate technical considerations across functions. Share platform knowledge, develop best practices, mentor colleagues, and promote continuous improvement. CMC strategy Cell and gene therapy platforms Cell-based therapeutics Biologics process development Analytical development Manufacturing process characterization Technology transfer Stability and control strategy External partner technical oversight Process improvement

Before you apply

Applying takes about a minute. These four things decide how fast it moves after that.

Your profile is current

It's what we read first. Occupations, seniority and locations matter more than a long history.

Two examples you can talk through

Not a portfolio — just two pieces of work where you can explain the decisions and what you'd change.

A number in mind

What you're on now and what would make you move. We negotiate better when we know both.

Your notice period

Employers plan around it, and it's the question that stalls offers most often.

Once you apply, someone reads it and calls you before anything reaches the employer — usually within two working days.

More like this