Postdoctoral Research Fellow - Valurupalli Lab

Responsibilities: Design, execute, and interpret a program of independent wet-lab research, with mentorship from the principal investigator. Develop and optimize experimental systems, including CRISPR screening platforms, glycoengineered cell models, and immune co-culture assays. Analyze complex, high-dimensional datasets in collaboration with computational scientists, and develop sufficient computational fluency to interrogate your own data. Present results at lab meetings, institutional forums, and national and international conferences. Prepare first-author manuscripts for publication and contribute to collaborative projects. Contribute to fellowship and grant applications and be supported in applying for independent funding (F32, K99/R00, and foundation awards).Mentor research associates, graduate students, and summer scholars, and contribute to a supportive lab culture.

Qualifications: PhD, MD, or MD/PhD in immunology, cancer biology, molecular biology, chemical biology, biochemistry, cell biology, or a related field. A record of productive, rigorous research, including at least one first-author publication or preprint. Strong hands-on experience in mammalian cell culture and molecular biology. Demonstrated ability to drive a project independently, troubleshoot, and think creatively about experimental design. Excellent written and verbal communication skills. Particularly relevant experience (not required):Primary human immune cell culture and functional immune assays (T cell, NK cell, or macrophage).CRISPR screening, including library design, screen execution, and analysis. Glycobiology, carbohydrate chemistry, or lectin-based methods. Cell surface or proximity-labeling proteomics and mass spectrometry. Antibody engineering, protein engineering, or CAR design. Advanced microscopy, including live-cell or super-resolution imaging. Programming in R or Python for the analysis of genomics or proteomics data. Environment and support Our lab sits within a highly collaborative scientific community. Fellows have access to Dana-Farber's clinical and translational infrastructure and patient samples, the Broad Institute's genomics, proteomics, and imaging platforms, and a wide network of collaborators across Harvard and MIT. Postdoctoral fellows receive salary and benefits per Dana-Farber Cancer Institute postdoctoral guidelines, along with dedicated support for conference travel, career development, and the transition to independence. At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply. Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.