Associate Principal Scientist, Liquid Chromatography-Mass Spectrometry (LCMS) Assay Development
$83,000.00 - $173,000.00
ApplyAssociate Principal Scientist, Liquid Chromatography-Mass Spectrometry (LCMS) Assay Development
Posted 18 days ago
SENIORITY
Lead
SALARY
$83,000.00 - $173,000.00
About the role
- Develop reliable extraction, chromatographic, and mass spectrometric analysis procedures for highly challenging and complex methods
- Document all project work according to Assay Development processes and procedures
- Communicate progress and status to the Director of Assay Development and Project Management, as necessary
- Present method development results at Prevalidation Committee Meetings
- Independently interact with Project Management and clients to provide project status updates, as necessary
- Guide Wet Lab staff through clear instructions and communication
- Provide clear method documentation to Project Management and support analytical staff during the method hand-off process
- Actively contribute to conference presentations and publications under PK/PD and biomarker analysis
- Master's Degree with 6-8 years' experience, or Ph.D. 2-5 yrs experience (industry experience preferred)
- Highly experienced in Liquid Chromatography-Mass Spectrometry and biologic sample preparation
- Advanced knowledge of chemistry involved in method development procedures
- Experience with regulated bioanalysis, method development, LBA/Liquid Chromatography-Mass Spectrometry, proteomics sample preparation, and automation
- Other Equivalent combination of education, training, and experience may be accepted in lieu of degree
- The Knowledge, Skills and Abilities Needed for This Role: Advanced knowledge in Liquid Chromatography-Mass Spectrometry theory and biologic sample preparation
- Knowledge of high resolution mass spectrometry, including Thermo Orbitraps, Exploris, and Excedions
- Knowledge of triple quadrupole systems, including Sciex 6500, 6500 plus, and 7500 plus
- Hands-on experience with clinical biomarker analysis
- Ability to develop and present well-organized Prevalidation Committee Meeting presentations
- Excellent attention to detail and communication skills
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