Medicinal Chemistry Project Leader

Posted 5 days ago

virtual vocationsNew York (NY)

SENIORITY

Manager

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About the role

Leading chemistry efforts within a cross-functional project team, the full-time Medicinal Chemistry Project Leader will drive PROTAC projects from inception to clinical candidate nomination, with a focus on degrader-antibody conjugates, in a hybrid work environment.
Key responsibilities: Drive milestone decision-making on assigned PROTAC projects in line with target product profiles and timelines Expeditiously design PROTACs and degrader-antibody conjugates using advanced computational chemistry resources Analyze complex datasets to generate new testable hypotheses and ensure effective collaboration with external CRO resources
Required qualifications: PhD in organic chemistry or medicinal chemistry with 8+ years of pharma/biotech drug discovery experience Proven track record of leading research projects through milestone decisions toward clinical candidate nomination Extensive experience in synthetic and medicinal chemistry, particularly with antibody-drug conjugates Deep understanding of pharmacokinetic principles and in vivo pharmacology Ability to effectively communicate project needs and strategies to multidisciplinary teams and senior leaders

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