Laboratory Technician - Immunoassays
chroniclebioDenver (CO)
About the role
About Chronicle Bio Chronicle Bio is a clinical-stage precision techbio company developing biomarker-guided treatments for ME/CFS, Long COVID, POTS, and related neuroimmune conditions. Our platform combines a large-scale biobank with an endotype-driven diagnostic and therapeutic strategy, allowing us to match existing and novel therapeutics to the specific drivers of each patient's disease. We are a mission-driven team aiming to lead discovery in the largest unmet needs in healthcare.
The Role:
Chronicle Bio seeks a Research Associate to run plate-based immunoassays on human biospecimens for our biomarker research programs. You will handle day-to-day assay execution, from sample prep through data QC and reporting. This bench-focused role suits someone who values clean technique, careful sample tracking, and reproducible data.
Key Responsibilities:
Run ELISAs and related immunoassays in duplicate according to kit inserts and internal SOPs, keeping incubation times and temperatures exact. Prepare buffers, standards, controls, and reagents; thaw, aliquot, and dilute plasma and serum samples. Lay out and wash plates (manually or with an automated washer), and pipette accurately with multichannel pipettes on a tight schedule. Read plates on a microplate reader, fit standard curves, calculate results, and apply QC criteria (curve fit, %CV, controls); re-run samples that fail QC or fall out of range. Keep sample inventory, chain of custody, reagent lot numbers, and raw data up to date in the LIMS/ELN; report status and issues to the supervising scientist. Help troubleshoot assays, and help onboard new kits or protocols as project needs change. Handle human biospecimens safely under BSL-2 and Universal Precautions.
What You Bring:
B.S. in Biology, Biochemistry, Immunology, or a related field, with 1+ year of hands-on lab experience. Proven experience running ELISAs or similar plate-based immunoassays end to end, including standard curve analysis in Excel, Prism, or similar software. Strong single- and multichannel pipetting skills; experience handling human plasma or serum under BSL-2.Attention to detail and reliable documentation and sample traceability.
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