Medical Director, Clinical Development

Department: 1240GL - Clinical Development

Education and Skills Requirements: Doctor of Medicine degree; board certification or advanced training in neurology, neuroscience, neuromuscular disease, pediatrics, internal medicine, or a related specialty preferred, or other relevant degree 5+ years of relevant experience, with 3+ years of clinical development, medical monitoring, pharmacovigilance, clinical research, or related roles within the pharmaceutical or biotechnology industry Experience serving as a medical monitor or providing medical oversight for interventional clinical trials Experience in rare disease, neuromuscular disease, genetic medicines, oligonucleotide therapeutics, or other complex therapeutic areas preferred Strong understanding of clinical trial design, protocol execution, medical data review, safety monitoring, and clinical development processes Working knowledge of FDA, EMA, ICH, GCP, and other applicable regulatory requirements for clinical trials Regulatory experience with Pre-lNDs, INDs, CTAs, EOP 2 meetings and NDA/BLAs/MAA, both US and ex-USExperience reviewing and contributing to clinical and regulatory documents, including protocols, informed consent forms, investigator brochures, clinical study reports, safety narratives, briefing materials, and regulatory responses Ability to interpret clinical, safety, biomarker, pharmacodynamic, and efficacy data and translate findings into clear medical recommendations Strong clinical judgment and ability to assess participant safety, protocol eligibility, adverse events, and medically complex study questions Demonstrated ability to work effectively in a fast-paced, matrixed biotechnology environment with cross-functional partners and external vendors Strong collaboration skills with the ability to influence without authority, build alignment, and drive practical solutions across teams Excellent written, verbal, and presentation skills, with the ability to communicate complex medical and scientific information clearly to internal and external audiences Strong attention to detail, organizational skills, and ability to manage multiple priorities while maintaining high-quality execution Ability to operate with appropriate independence, sound judgment, urgency, and accountability Experience working with CROs, investigators, study sites, and external experts preferred Willingness to be hands-on and contribute across strategic and executional activities in a growing clinical-stage biotechnology company Ability to travel as needed for investigator meetings, site engagement, advisory boards, congresses, and internal meetings#LI-OnsiteMA Pay Range$270,000—$310,000 USDThe pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills. The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload. Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law. BACK | NEXT