Senior Scientific Applications Scientist — Pharmaceutical Informatics

Rockville, Maryland | Full-time | Hybrid: 2–3 days per week in the office Annual base salary: $150,000–$190,000 USD. This position offers the benefits listed below and does not include bonus, commission or equity compensation. Insilica builds software that helps scientists find, evaluate and use chemical and biological evidence. We are hiring a senior scientific applications scientist to lead our work with pharmaceutical clients: turning their research and safety questions into useful, source-linked workflows and successful pilots. What you will own • Lead technical engagements with pharmaceutical clients from start to finish: scope the work, agree success criteria, run the pilot, and present results to the client's scientific leadership. • Work directly with pharmaceutical and life-sciences scientists to define the question, evidence requirements and criteria for a useful result. • Build or prototype scientific workflows using Python, structured data, literature evidence and computational tools. • Check chemical identity, assay context, units, study quality and the applicability of model predictions. • Evaluate AI-assisted summaries against their original sources and explain uncertainty clearly. • Deliver demonstrations, pilot workflows and reusable report templates, working closely with engineering. • Translate customer feedback into specific product requirements and support adoption. What you bring • Several years (typically 5 or more) in pharma, biotech, a CRO, consulting or scientific software, including leading technical work directly with pharmaceutical clients or senior scientific stakeholders. • Development experience or substantial computational experience, demonstrated through reproducible scientific analyses, scripts, notebooks or workflow tools you personally built and validated. • Practical scientific informatics experience in pharmaceutical research, ADME/toxicology, nonclinical safety or a closely related setting. • Demonstrated ability to analyze chemical or biological data and inspect computational results critically. • Confidence leading conversations with customers and explaining conclusions and limitations. • Scientific programming skills and experience making an analysis reproducible. • Evidence of delivering useful work collaboratively with scientists and software engineers. Industry or consulting experience leading client-facing scientific work is required; advanced scientific training is useful. Knowledge of cheminformatics, evidence synthesis, ontologies or predictive toxicology is helpful. In your application, describe a client or stakeholder engagement you led, the scientific workflow behind it, how you checked its validity and how people used the result. Share public or sanitized work only. Please include a public or sanitized example of your development or computational work and explain your own contribution. Current benefits Our current standard benefits include medical, dental and vision insurance with employer premium contributions; employer-paid basic life insurance; HSA and health FSA options with employer contributions for eligible participants; and a 401(k) retirement plan. We provide 80 hours of paid vacation and 80 hours of paid sick leave annually, plus 10 paid holidays, under the applicable policies. Benefits are subject to eligibility and plan terms.