Director, Organic Chemistry

Responsibilities: Design and execute complex, multistep small-molecule syntheses Develop and synthesize metal chelators, fluorophores, linkers and related conjugates Troubleshoot difficult reactions independently using a first-principles scientific approach Optimize reaction conditions, purification methods, yields and reproducibility Characterize compounds using techniques including NMR, LC-MS and HPLC Maintain accurate experimental records and communicate results clearly Support process development, scale-up and technology transfer activities Collaborate across discovery, development and manufacturing Remain actively involved at the laboratory bench

Qualifications: PhD in Organic Chemistry, Medicinal Chemistry or a closely related discipline preferred Strong hands-on experience in synthetic organic chemistry Demonstrated experience designing or synthesizing metal chelators Demonstrated experience in fluorophore or fluorescent-probe chemistry, ideally including bioconjugation Proven ability to solve difficult synthetic and purification problems independently Experience with complex multistep synthesis and route development Strong analytical, organizational and scientific communication skills